Université Catholique de Louvain, using crystals to get the right (or left) compound

Our Belgian partners are experts in creating highly interesting enantiopure compounds through a chemical process known as deracemisation. If you want to know more details, keep reading.

IMPACTIVE celebrates its second annual meeting in Cagliari

After our second year of collaboration, the IMPACTIVE project partners have celebrated their second general assembly in Cagliari, hosted by the Italian partner CSGI. The discussions focused on setting our priorities for the next two years, as well as sharing the progress we have made over the past year.

University of Montpellier, leading IMPACTIVE and lab synthesis

Our project leader, the University of Montpellier, juggles many tasks. They coordinate smooth collaboration among partners, while leading the development of innovative mechanochemical methods at a lab scale.

Bead milling for paracetamol, a mechanochemical success

The IMPACTIVE team has investigated the manufacturing of the popular drug paracetamol using mechanochemistry. For the first time we accomplished the use of bead-milling technology for the solvent-free synthesis of the medicine, outperforming traditional solution-based methods.

Join IMPACTIVE at ESOF2024 event this month!

On 13 and 14 June, IMPACTIVE will attend the EuroScience Open Forum 2024, held in Poland, with an exciting session about green pharma.

Active Pharmaceutical Ingredients (APIs), the aim of IMPACTIVE

An API is the essential component responsible for the therapeutic effect of a medicine. This crucial element can be sourced from various methods. In this article we explore what APIs are, why are they important, and the strict regulations they face to ensure their quality and safety in pharmaceutical production worldwide.

Mechanochemistry could provide a safer and greener route to anticancer drugs

The IMPACTIVE team has looked into the manufacturing of imatinib: an anticancer drug on the Essential Medicines’ list of the Worlds’ Health Organisation. Thanks to mechanochemistry, we discovered a synthetic route to do it in a way that is safer, greener and more efficient than the commercial method used nowadays.

Mechanochemistry: pioneering green synthesis solutions across industries

Mechanochemistry is a groundbreaking field, revolutionizing chemistry through force-triggered reactions, eco-friendly practices, and efficient processes. It’s a pioneer technology with applications across multiple fields: biomass transformation, energy storage, agrochemicals, and much more. With its versatility and sustainability, it’s reshaping a myriad of industries towards a greener, more innovative future. Keep reading to unveil different use-cases.

Who is behind IMPACTIVE? Discover our partners!

IMPACTIVE is a very ambitious project, with members of the greatest background diversity. Altogether, we want to get rid of the solvents in the current pharmaceutical processes and substitute them with mechanochemistry, a greener, more sustainable approach.

IMPACTIVE celebrates its annual meeting in Lisbon

After twelve months of collaboration, the IMPACTIVE project partners have celebrated a meeting in Lisbon, hosted by Portuguese partner IST-ID. The discussions delved into the developments of new mechanochemical methods, as well as useful strategies towards the protection of intellectual property towards commercialisation.