Mechanochemistry towards greener pharmaceuticals

Innovative processes to revolutionise how we manufacture drugs and chemicals

Greener pharma

The pharmaceutical industry generates tons of toxic waste and carbon emissions. Moreover, it often relies on the supply chains of chemicals and catalysts, which limits timely production during emergencies.

Read More


Mechanochemistry gets rid of solvents. It uses mechanical force, like grinding and milling, to drive chemical reactions. It’s succesfully used by other industrial sectors (aerospace, cosmetics, fertilisers…). Now, IMPACTIVE will validate its use in pharma.

Read More

An impactful solution

IMPACTIVE is a project funded by the European Commission, which counts on 17 partners in 10 different countries. Our expertise covers the whole value chain, from research to industry and innovation, which will ensure our solutions find ways to market.

Read More

Strong industrial collaboration

IMPACTIVE counts with the industry from the start. 2 international companies (Merck & Novartis) are part of the project, to help with the scaling up.

Join IMPACTIVE at ESOF2024 event this month!

On 13 and 14 June, IMPACTIVE will attend the EuroScience Open Forum 2024, held in Poland, with an exciting session about green pharma.

Read more

Active Pharmaceutical Ingredients (APIs), the aim of IMPACTIVE

An API is the essential component responsible for the therapeutic effect of a medicine. This crucial element can be sourced from various methods. In this article we explore what APIs are, why are they important, and the strict regulations they face to ensure their quality and safety in pharmaceutical production worldwide.

Read more

Mechanochemistry could provide a safer and greener route to anticancer drugs

The IMPACTIVE team has looked into the manufacturing of imatinib: an anticancer drug on the Essential Medicines’ list of the Worlds’ Health Organisation. Thanks to mechanochemistry, we discovered a synthetic route to do it in a way that is safer, greener and more efficient than the commercial method used nowadays.

Read more