Mechanochemistry towards greener pharmaceuticals

Innovative processes to revolutionise how we manufacture drugs and chemicals

Greener pharma

The pharmaceutical industry generates tons of toxic waste and carbon emissions. Moreover, it often relies on the supply chains of chemicals and catalysts, which limits timely production during emergencies.

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Mechano…what?

Mechanochemistry gets rid of solvents. It uses mechanical force, like grinding and milling, to drive chemical reactions. It’s succesfully used by other industrial sectors (aerospace, cosmetics, fertilisers…). Now, IMPACTIVE will validate its use in pharma.

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An impactful solution

IMPACTIVE is a project funded by the European Commission, which counts on 17 partners in 10 different countries. Our expertise covers the whole value chain, from research to industry and innovation, which will ensure our solutions find ways to market.

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Strong industrial collaboration

IMPACTIVE counts with the industry from the start. 2 international companies (Merck & Novartis) are part of the project, to help with the scaling up.

University of Montpellier, leading IMPACTIVE and lab synthesis

Our project leader, the University of Montpellier, juggles many tasks. They coordinate smooth collaboration among partners, while leading the development of innovative mechanochemical methods at a lab scale.

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Bead milling for paracetamol, a mechanochemical success

The IMPACTIVE team has investigated the manufacturing of the popular drug paracetamol using mechanochemistry. For the first time we accomplished the use of bead-milling technology for the solvent-free synthesis of the medicine, outperforming traditional solution-based methods.

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Join IMPACTIVE at ESOF2024 event this month!

On 13 and 14 June, IMPACTIVE will attend the EuroScience Open Forum 2024, held in Poland, with an exciting session about green pharma.

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