Mechanochemistry towards greener pharmaceuticals

Innovative processes to revolutionise how we manufacture drugs and chemicals

Greener pharma

The pharmaceutical industry generates tons of toxic waste and carbon emissions. Moreover, it often relies on the supply chains of chemicals and catalysts, which limits timely production during emergencies.

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Mechano…what?

Mechanochemistry gets rid of solvents. It uses mechanical force, like grinding and milling, to drive chemical reactions. It’s succesfully used by other industrial sectors (aerospace, cosmetics, fertilisers…). Now, IMPACTIVE will validate its use in pharma.

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An impactful solution

IMPACTIVE is a project funded by the European Commission, which counts on 17 partners in 10 different countries. Our expertise covers the whole value chain, from research to industry and innovation, which will ensure our solutions find ways to market.

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Strong industrial collaboration

IMPACTIVE counts with the industry from the start. 2 international companies (Merck & Novartis) are part of the project, to help with the scaling up.

What the waste? Shaping sustainability in the chemical industry with mechanochemistry

Solvents are well-known pollutants that pose significant waste management and health concerns. Such pollution problems have led to increasing restrictions on solvent use, as reflected by the recent US legislation on dichloromethane, published in May 2024. In this context, mechanochemistry could reshape the industry, supplying the world with pharmaceutical products while avoiding the use of toxic solvents.

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Back to basics: types and uses of solvents

There are as many solvents as there are uses for them: from cosmetics to the textile industry, through pharmaceutical manufacturing to oil production. The history of chemistry is, in part, a chronicle of the discovery and development of these substances over time, until now: their application is increasingly restricted, which has led to the emergence of greener alternatives, such as mechanochemistry.

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Register for the first IMPACTIVE webinar!

We’re launching our IMPACTIVE webinar series to discuss mechanochemistry, green pharmaceuticals, and green chemistry. Save the date: our first session will take place on 28 May at 12:00 pm (noon) CEST, with a presentation by Evelina Colacino, our project coordinator.

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