Radboud University, developing new solventless reactions

Our researchers from Radboud University are at the core of IMPACTIVE. This team works on exploring new reactions to synthesise pharmacologically active compounds at a lab scale while avoiding the use of solvents.

Mechanochemistry could provide a safer and greener route to anticancer drugs

The IMPACTIVE team has looked into the manufacturing of imatinib: an anticancer drug on the Essential Medicines’ list of the Worlds’ Health Organisation. Thanks to mechanochemistry, we discovered a synthetic route to do it in a way that is safer, greener and more efficient than the commercial method used nowadays.

IMPACTIVE
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