Our project leader, the University of Montpellier, juggles many tasks. They coordinate smooth collaboration among partners, while leading the development of innovative mechanochemical methods at a lab scale.
The IMPACTIVE team has investigated the manufacturing of the popular drug paracetamol using mechanochemistry. For the first time we accomplished the use of bead-milling technology for the solvent-free synthesis of the medicine, outperforming traditional solution-based methods.
The IMPACTIVE team has looked into the manufacturing of imatinib: an anticancer drug on the Essential Medicines’ list of the Worlds’ Health Organisation. Thanks to mechanochemistry, we discovered a synthetic route to do it in a way that is safer, greener and more efficient than the commercial method used nowadays.
IMPACTIVE is a very ambitious project, with members of the greatest background diversity. Altogether, we want to get rid of the solvents in the current pharmaceutical processes and substitute them with mechanochemistry, a greener, more sustainable approach.
